Ocular Surface Changes in patients with Type 2 Diabetes Mellitus: Evidence from Palestine

Doi: 10.36351/pjo.v41i3.2020

Authors

  • Mohammed A.M Aljarousha
  • Ahmed Mohamed Osman
  • Emad IH Shaqoura
  • Iman Farajallah
  • Nahdiyah Azman

DOI:

https://doi.org/10.36351/pjo.v41i3.2020

Abstract

Purpose:  To determine the ocular surface disease in patients with Type 2 diabetes mellitus (DM) by using translated and validated Arabic version of Ocular Surface Disease Index (Arab-OSDI) and the clinical measurements.

Study Design:  Cross-sectional study.
Methods:  A total of 30 patients with Type 2DM and 30 non-diabetic controls were included in this study. All participants, who were non-contact lens users, completed the Arab-OSDI questionnaire and underwent clinical evaluations including tear break-up time (BUT), meibomian gland assessments, tear meniscus height (TMH), Marx line (ML), Schirmer II tear test, fluorescein corneal staining (F/S), and lissamine green conjunctival staining (LGS) were recruited. Dry eye (DE) was diagnosed when Arab-OSDI scores were ≥13 and BUT was <5 seconds.

Results:  The DM and non-DM groups demonstrated notable differences in the outcomes of Arab-OSDI (p = 0.017) and the evaluations of meibomian gland (p = 0.022). Within the DM group, individuals with dry eye showed significantly elevated Arab-OSDI results compared to those without dry eye (p = 0.014), whereas the other clinical parameters showed no statistically significant differences.

Conclusion:  Individuals with Type-2 DM may experience damage to the lacrimal functional unit, leading to tear deficiency or evaporative DE. This altered tear composition may increase DE symptoms, as reflected in elevated Arab-OSDI scores.

Keywords:  Ocular surface disease, Diabetes Mellitus, Ocular surface disease index.

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Published

01-07-2025

How to Cite

1.
Mohammed A.M Aljarousha, Ahmed Mohamed Osman, Emad IH Shaqoura, Iman Farajallah, Nahdiyah Azman. Ocular Surface Changes in patients with Type 2 Diabetes Mellitus: Evidence from Palestine: Doi: 10.36351/pjo.v41i3.2020. pak J Ophthalmol [Internet]. 2025 Jul. 1 [cited 2025 Jul. 1];41(3). Available from: https://www.pjo.org.pk/index.php/pjo/article/view/2020

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Original Articles