Role of Tetracycline in Corneal Neovascularization

Authors

  • Arshad Ali Lodhi, Murtaza, Munawar Ahmed , Noman Ahmed Ghulam Haider, Sameen Afzal Junejo, Mustafa Kamal

DOI:

https://doi.org/10.36351/pjo.v31i3.178

Abstract

Purpose: To find the efficacy of topical tetracycline in corneal neovascularization.
Material and Methods: In this prospective observational clinical analysis,
patients more than fifteen year’s age of either sex were enrolled. Anterior
segment slit lamp examination was performed. Fluorescein 1% dye and rose
bengal were used to stain cornea at the bed and margins simultaneously. The
area of corneal vascularization was measured in mm using 0.5% fluorescein
dye. The percentage of neovascularized corneal areas to the entire cornea was
calculated.
Result: Out of twenty eight patients twenty one completed follow up period of
four months. Among 21 patients males were 10 (47.6%), and females 11
(52.38%) with unilateral and bilateral corneal neo-vascularization. 15 (71.42%)
responded well and showed reduction in corneal new vessels from 7 mm pretreatment
to 2 mm (overall) post treatment at the end of fourth month. six patient
showed poor or no response due to extended fibrosis.
Conclusion: Topical tetracycline has remained quite instrumental in reducing
superficial epithelial and sub-epithelial corneal new vessels.
Key Words: Cornea; Neovascularization; Tetracycline; Therapeutic effect

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Published

30-09-2015

How to Cite

1.
Sameen Afzal Junejo, Mustafa Kamal AALMMA , NAGH. Role of Tetracycline in Corneal Neovascularization. pak J Ophthalmol [Internet]. 2015 Sep. 30 [cited 2024 Mar. 29];31(3). Available from: https://www.pjo.org.pk/index.php/pjo/article/view/178

Issue

Section

Review Articles