Cranial Nerve Palsies as Initial Presentation of Acute Lymphoblastic Leukemia – A Case Report

Doi: 10.36351/pjo.v39i3.1635

Authors

  • Muhammad Sohail Ajmal Ghoauri
  • Nauman Ismat Butt
  • Dur-e-Sabeeh
  • Muhammad Bilal Rasheed
  • Muhammad Umair Javed

DOI:

https://doi.org/10.36351/pjo.v39i3.1635

Abstract

The clinical manifestations of acute leukemia are diverse and can range from asymptomatic to life-threatening Complications.1 Cranial nerve palsies as a presenting feature of this disease is relatively rare. It can be attributed to leukemic infiltration of cranial nerves, or the development of cranial nerve palsies secondary to intracranial complications such as subdural hematoma. Our patient presented with 4-month history of progressively worsening eye and visual disturbances. On examination, there was bilateral ptosis and proptosis. The right pupil was dilated and non-responsive to light with complete blindness. Left pupil had a sluggish response to light and had decreased visual acuity. There was 6th nerve palsy on left side and bilateral sensorineural hearing loss. Bone marrow biopsy showed Acute Lymphoblastic Leukemia. He was diagnosed with Acute Lymphoblastic Leukemia with brain (CNS) infiltration causing 2nd, 3rd, 6th and 8th cranial nerve palsies.

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Published

30-06-2023

How to Cite

1.
Ghoauri MSA, Butt NI, Dur-e-Sabeeh, Rasheed MB, Javed MU. Cranial Nerve Palsies as Initial Presentation of Acute Lymphoblastic Leukemia – A Case Report: Doi: 10.36351/pjo.v39i3.1635. pak J Ophthalmol [Internet]. 2023 Jun. 30 [cited 2024 Jul. 14];39(3). Available from: https://www.pjo.org.pk/index.php/pjo/article/view/1635

Issue

Section

Case Report