Comparison of Intralesional Triamcinolone Acetonide Injection versus Surgical Intervention for Management of Primary Chalazion

Doi: 10.36351/pjo.v38i4.1457

Abstract

Purpose:  To compare the effectiveness of intralesional steroid injection versus Incision and curettage in management of primary chalazion.

Study Design:  Quasi experimental study.

Place and Duration of Study:  Department of Ophthalmology, Pakistan Institute of Medical Sciences, Islamabad, from August 2020 to January 2021.

Methods:  Eighty patients were divided into two groups of 40 each through consecutive sampling. Patients with primary chalazion of the size >5mm, age group 18 to 50 years and either gender were included. Patients with recurrent, multiple and infected chalazia were excluded. All patients underwent complete ocular examination. Group A underwent Incision and curettage while in group B a 28 gauge needle with a 1 ml syringe was used to inject 0.25 ml of 40 mg/ml Triamcinolone Acetonide into the chalazion via transcutaneous route. Success was defined as 80% reduction in the size of chalazion after one month. The chi-square test was used for equivalence of treatment efficacy between the groups.

Results:  Age range in this study was 18 to 50 years. Mean age was 34.10 ± 5.87 years in Group A and 35.975 ± 7.60 years in Group B. The procedure was successful in 31 (77.5%) individuals in group A and 33 (82.5%) individuals in group B (P = 0.576), which was statistically insignificant. Stratification with respect to gender and age also showed no statistically significant difference between the two groups (p > 0.05).

Conclusion:  Intralesional steroid injection and Incision/curettageare equally effective in management of primary chalazion.