Acute Rhino-orbital-cerebral Mucormycosis in a Patient with COVID – 19

Doi: 10.36351/pjo.v38i1.1301


  • Warda Ali Naqvi Shifa International Hospital, Islamabad
  • Muhammad Javid Bhutta Shifa International Hospital, Islamabad
  • Ejaz Ahmed Khan Shifa International Hospital, Islamabad
  • Aftab Akhtar Shifa International Hospital, Islamabad
  • Sania Raza Shifa International Hospital, Islamabad



mucormycosis, covid-19, fungal infections


COVID-19 patients are known to have immunosuppression due to decreased lymphocytes and increased susceptibility to co-infections (Bacterial and fungal). We present a case of 61-year-old patient who had diabetes, hypertension and ischemic heart disease with COVID-19 infection admitted after RT-PCR positive result. He developed rhino-orbital Mucormycosis during treatment. He received Remdesivir with parenteral Methylprednisolone and Meropenem. While admitted in the ward, he developed signs of orbital cellulitis. Magnetic resonance imaging (MRI) of the brain, orbits, and paranasal sinuses revealed right frontal, ethmoidal, and maxillary sinusitis with the extension of the sinisuidal disease to the orbit. A nasal biopsy revealed broad aseptate filamentous fungal hyphae suggestive of Mucormycosis. Long-term use of steroids/monoclonal antibodies/broad-spectrum antibiotics may contribute to the predisposition to fungal disease. Early diagnosis and prompt management are warranted to avoid morbidity.

Key Words:  Mucormycosis, COVID – 19, Orbital Cellulitis.




How to Cite

Naqvi WA, Bhutta MJ, Khan EA, Akhtar A, Raza S. Acute Rhino-orbital-cerebral Mucormycosis in a Patient with COVID – 19: Doi: 10.36351/pjo.v38i1.1301 . pak J Ophthalmol [Internet]. 2021 Dec. 31 [cited 2024 Jul. 16];38(1). Available from:



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