Vitreo-macular Interface Abnormalities in Diabetic and Non-Diabetic Patients Using Optical Coherence Tomography

Doi: 10.36351/pjo.v36i3.1018

Authors

  • Uzma Hamza Assisstant Professor Ophthalmology,Allama Iqbal Medical College/ Jinnah Hospital Lahore
  • Waqas Asghar Medical Officer, Eye Department, Allama Iqbal Medical College/ Jinnah Hospital Lahore
  • Qasim Lateef Chaudhry Associate Professor Ophthalmology, Allama Iqbal Medical College/ Jinnah Hospital Lahore
  • Muhammad Hassaan Ali Senior Registrar Ophthalmology, Allama Iqbal Medical College/ Jinnah Hospital Lahore
  • Sana Jahangir Fellow of Vitreoretina, Eye Department, Allama Iqbal Medical College/ Jinnah Hospital Lahore

DOI:

https://doi.org/10.36351/pjo.v36i3.1018

Keywords:

Vitreomacular interface abnormalities, optical coherence tomography, epiretinal membrane, vitreomacular traction.

Abstract

Purpose: To study the frequency of vitreomacular interface abnormalities (VIAs) in diabetic and non-diabetic
patients presenting in a tertiary care hospital.
Study Design: Comparative cross-sectional study.
Place and Duration of Study: Jinnah hospital, Lahore from May 2013 to June 2016.
Methods: The frequency of vitreomacular interface abnormalities (VIAs) was assessed among 278 patients, who
presented in outpatient department of our hospital. Patients were categorized into diabetic and non-diabetic
groups on the basis of hemoglobinHbA1c. Patients with altered macular reflex on slit lamp examination underwent
spectral domain (SD) optical coherence tomography (OCT) of macula to determine VIAs.
Results: There were 278 patients in the study with mean age 59.7 ± 11.7(range: 40 – 65) years and male to
female ratio of 1:1.06. Prevalence of VIAs was observed to be higher among diabetic patients than non-diabetics
in all age groups (p-value < 0.05). Overall frequency of different VIAs was found to be 10.7% for epiretinal
membrane, 6.4% for posterior vitreous detachment, 6.1% for macular edema/macular cyst, 4.3% for
vitreomacular traction, 1.8% for full thickness macular holes and 0.71% for partial thickness macular holes.
Macular edema/macular cystwas the most common. VIA was more commonly observed in diabetic patients
(17.2%). Except for ERM, all lesions of VIAs were significantly more prevalent in females as compared to males.
Conclusion: VIAs are found in significantly larger number in diabetics compared to non-diabetic patients.
Female gender with advancing age is associated with a higher frequency of VIAs.

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Published

04-05-2020

How to Cite

1.
Hamza U, Asghar W, Chaudhry QL, Ali MH, Jahangir S. Vitreo-macular Interface Abnormalities in Diabetic and Non-Diabetic Patients Using Optical Coherence Tomography: Doi: 10.36351/pjo.v36i3.1018. pak J Ophthalmol [Internet]. 2020 May 4 [cited 2024 Mar. 28];36(3). Available from: https://www.pjo.org.pk/index.php/pjo/article/view/1018

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Original Articles