@article{Hamza_Asghar_Chaudhry_Ali_Jahangir_2020, title={Vitreo-macular Interface Abnormalities in Diabetic and Non-Diabetic Patients Using Optical Coherence Tomography: Doi: 10.36351/pjo.v36i3.1018}, volume={36}, url={https://www.pjo.org.pk/index.php/pjo/article/view/1018}, DOI={10.36351/pjo.v36i3.1018}, abstractNote={<p>Purpose: To study the frequency of vitreomacular interface abnormalities (VIAs) in diabetic and non-diabetic<br>patients presenting in a tertiary care hospital.<br>Study Design: Comparative cross-sectional study.<br>Place and Duration of Study: Jinnah hospital, Lahore from May 2013 to June 2016.<br>Methods: The frequency of vitreomacular interface abnormalities (VIAs) was assessed among 278 patients, who<br>presented in outpatient department of our hospital. Patients were categorized into diabetic and non-diabetic<br>groups on the basis of hemoglobinHbA1c. Patients with altered macular reflex on slit lamp examination underwent<br>spectral domain (SD) optical coherence tomography (OCT) of macula to determine VIAs.<br>Results: There were 278 patients in the study with mean age 59.7 ± 11.7(range: 40 – 65) years and male to<br>female ratio of 1:1.06. Prevalence of VIAs was observed to be higher among diabetic patients than non-diabetics<br>in all age groups (p-value < 0.05). Overall frequency of different VIAs was found to be 10.7% for epiretinal<br>membrane, 6.4% for posterior vitreous detachment, 6.1% for macular edema/macular cyst, 4.3% for<br>vitreomacular traction, 1.8% for full thickness macular holes and 0.71% for partial thickness macular holes.<br>Macular edema/macular cystwas the most common. VIA was more commonly observed in diabetic patients<br>(17.2%). Except for ERM, all lesions of VIAs were significantly more prevalent in females as compared to males.<br>Conclusion: VIAs are found in significantly larger number in diabetics compared to non-diabetic patients.<br>Female gender with advancing age is associated with a higher frequency of VIAs.</p>}, number={3}, journal={Pakistan Journal of Ophthalmology}, author={Hamza, Uzma and Asghar, Waqas and Chaudhry, Qasim Lateef and Ali, Muhammad Hassaan and Jahangir, Sana}, year={2020}, month={May} }